Patrick Dempsey named People's Sexiest Man Alive.

Dethroning Chris Evans and triumphing over other contenders.

Dempsey grateful for the honor at this stage of life.

Rise to fame as Dr. Derek "McDreamy" on "Grey's Anatomy."

Upcoming projects include "Ferrari" and "Thanksgiving."

Dempsey's humor and humility about the recognition.

People magazine cover featuring Dempsey hits newsstands on Friday.